Efficacy and safety of Siponimod in SPMS

So  here we have it an drug with an effect on SPMS that slows progression in a phase III trial So this is good news.
The bad news I guess, is that the drug only slowed the rate of 3 month progression by 22% over so disease was not halted and an effect on 25 foot walking was not apparent and at the end of the study about 18% decided to withdraw which must mean that they were dissatisfied with the outcome.

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